1
Domain Presence / Absence
Build a domain presence/absence matrix across taxa. Continue to high-resolution profiling when ready.
New here? Try a ready-made example profile →
·
Want to split a family into its paralog groups?
Go to high-resolution profiling ↓
Filters
Comma separated. Multiple entries build multi-column matrix.
Or upload a file (one ID per line)
Querying database…
Presence / Absence Matrix
Cell values = distinct proteins. Rows = organisms, columns = profiles.
?
Families with similar presence/absence patterns across
organisms tend to be functionally linked — same pathway,
same complex, or lost together. That is the inference
phylogenetic profiling exists to support, so alongside a summary
of the matrix this ranks the most similar pairs of profiles.
Similarity is the Jaccard index: organisms carrying both families, over organisms carrying either. 1.00 means the two are always present and absent together.
Families present in every organism (or none) are left out — they match everything and carry no linkage signal.
Similarity is the Jaccard index: organisms carrying both families, over organisms carrying either. 1.00 means the two are always present and absent together.
Families present in every organism (or none) are left out — they match everything and carry no linkage signal.
Clustered Heatmap
Co-occurrence results
Domains co-occurring on the same proteins as the selected profile, ranked by frequency. The query profile itself is excluded.
Domain architecture patterns, ranked by frequency.